Exhibit 21.1

Subsidiaries

Jurisdiction of Incorporation

Desktop Metal Operating, Inc.

Delaware

Desktop Metal GMBH

Germany

Desktop Metal Securities Corporation

Massachusetts

addLEAP AB

Sweden

Figur Machine Tools LLC

New Jersey

EnvisionTEC US LLC

Delaware

Envisiontec GmbH

Germany

EnvisionTec Group Canada, Inc.

Canada

Adaptive3D LLC

Delaware

Adaptive 3D Technologies, LLC

Texas

Syzygy Memory Plastics Corporation

Delaware

Beacon Bio, Inc.

Delaware

DM Belgium B.V.

Belgium

Aerosint S.A.

Belgium

Dental Arts Laboratories, Inc.

Illinois

A.I.D.R.O. Srl

Italy

Meta Additive Ltd.

United Kingdom

Larry Brewer Dental Lab, Inc.

Oklahoma

Brewer Tafla Dental Technologies, LLC

Oklahoma

May Dental Arts, LLC

Missouri

ExOne Americas, LLC

Delaware

ExOne Operating, LLC

Delaware

ExOne GmbH

Germany

ExOne KK

Japan

Desktop Labs, Inc.

Delaware